Wednesday, June 4, 2008

A jug of red wine and 90 becomes the new 50



Eartha Kitt at 80 sets a tough standard. Image from Wikipedia

Is red wine the fountain of youth? I'm not suggesting that the divine Ms. Kitt relies on that elixer for her youthful appearance. But a handful of articles came across my desk today touting the potential of a resveratrol, a substance found in red wine, to keep people's hearts and bodies young.

All were based on two studies that found resveratrol kept aging mice healthy, middle aged, and slim in much the same way severe calorie restriction, a much less attractive way to maintain youthful vigor, does.

One of those studies came from Madison's LifeGen Technologies and the University of Wisconsin. (Barger JL, Kayo T, Vann JM, Arias EB, Wang J, et al. (2008) A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice.)

You'd have to drink a lot of wine to stay as young as the mice--the equivalent of 1,000 bottles a day. I'm thinking that after the first one, you might stop caring much.

The New York Times takes a balanced view, pointing out that the findings are interesting but there never is a panacea; that it's way too soon to understand what the research means for people; and that one reason for the interest is the enormous potential for a pharmaceutical company to clean up on this "longevity elixer."

The Reuters article focuses on potential protection to heart health.

The Atlanta Journal Constitution version homes in on the vanity angle, asking "is 90 the new 50?" and providing photos of well-aged celebrities such as Sean Connery, Kitt, and Sophia Loren. David Sinclair of Harvard Medical School, author of the second lab research report, admits to supplementing his diet with resveratrol. But he reminds readers that the most effective way to improve longevity is exercise.

I wonder what the desire for a magic fountain-of-youth pill that keeps us slim, healthy, and young without really trying does to the way we spend our healthcare dollars. And continuing to raise the bar for expectations of sustained youthfulness seems to serve product manufacturers more than it does the rest of us.

I don't know about you, but I'm having enough trouble keeping up with 50-something being the new 40-something!

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